Document Detail


Electromagnetic interference with implantable cardioverter-defibrillators at power frequency: an in vivo study.
MedLine Citation:
PMID:  24163067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The number of implantable cardioverter-defibrillators (ICDs) for the prevention of sudden cardiac death is continuing to increase. Given the technological complexity of ICDs, it is of critical importance to identify and control possible harmful electromagnetic interferences between various sources of electromagnetic fields and ICDs in daily life and occupational environments.
METHODS AND RESULTS: Interference thresholds of 110 ICD patients (1-, 2-, and 3-chamber ICDs) were evaluated in a specifically developed test site. Patients were exposed to single and combined electric and magnetic 50-Hz fields with strengths of up to 30 kV·m⁻¹ and 2.55 mT. Tests were conducted considering worst-case conditions, including maximum sensitivity of the device or full inspiration. With devices being programmed to nominal sensitivity, ICDs remained unaffected in 91 patients (83%). Five of 110 devices (5%) showed transient loss of accurate right ventricular sensing, whereas 14 of 31 (45%) of the 2- and 3-chamber devices displayed impaired right atrial sensing. No interference was detected in 71 patients (65%) within the tested limits with programming to maximum sensitivity, whereas 20 of 110 subjects (18%) exhibited right ventricular disturbances and 19 of 31 (61%) subjects exhibited right atrial disturbances.
CONCLUSIONS: Extremely low-frequency daily-life electromagnetic fields do not disturb sensing capabilities of ICDs. However, strong 50-Hz electromagnetic fields, present in certain occupational environments, may cause inappropriate sensing, potentially leading to false detection of atrial/ventricular arrhythmic events. When the right atrial/right ventricular interferences are compared, the atrial lead is more susceptible to electromagnetic fields.
CLINICAL TRIAL REGISTRATION URL: http://clinicaltrials.gov/ct2/show/NCT01626261. Unique identifier: NCT01626261.
Authors:
Andreas Napp; Stephan Joosten; Dominik Stunder; Christian Knackstedt; Matthias Zink; Barbara Bellmann; Nikolaus Marx; Patrick Schauerte; Jiri Silny
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-10-25
Journal Detail:
Title:  Circulation     Volume:  129     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-01-28     Completed Date:  2014-05-27     Revised Date:  2014-11-13    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  441-50     Citation Subset:  AIM; IM    
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT01626261
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MeSH Terms
Descriptor/Qualifier:
Activities of Daily Living*
Adult
Aged
Arrhythmias, Cardiac / physiopathology,  therapy*
Death, Sudden, Cardiac / prevention & control
Defibrillators, Implantable / adverse effects*
Electromagnetic Fields / adverse effects*
Electrophysiologic Techniques, Cardiac
Female
Heart Atria / physiopathology
Heart Ventricles / physiopathology
Humans
Male
Middle Aged
Occupational Exposure / adverse effects*
Retrospective Studies
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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