Document Detail

Electrolyte and water balance in cardiac insufficiency. Recent clinical and experimental data.
MedLine Citation:
PMID:  6992767     Owner:  NLM     Status:  MEDLINE    
The reasons for the disturbances of electrolyte and water balance in cardiac failure are not yet clarified. The decrease of cardiac output in cardiac insufficiency causes humoral regulatory mechanisms such as increased activity of the renin angiotensin-aldosterone system and increased secretion of antidiuretic hormone. These mechanisms in turn lead to an enhancement of renal sodium and water reabsorption. The humoral disturbances can be interpreted as ineffective regulatory mechanisms for hemodynamic changes in cardiac insufficiency; in fact, the humoral disturbances increase cardiac failure. In addition, an increased sodium content of the arteries may contribute to the hemodynamic changes in cardiac insufficiency.
K Hayduk; G Riegger; A Hepp
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Basic research in cardiology     Volume:  75     ISSN:  0300-8428     ISO Abbreviation:  Basic Res. Cardiol.     Publication Date:    1980 Jan-Feb
Date Detail:
Created Date:  1980-08-15     Completed Date:  1980-08-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0360342     Medline TA:  Basic Res Cardiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  289-93     Citation Subset:  IM    
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MeSH Terms
Aldosterone / secretion
Angiotensin II / blood
Arteries / physiopathology
Cardiac Output
Enzyme Inhibitors
Heart Failure / physiopathology*
Renin / secretion
Vascular Resistance / drug effects
Vasoconstriction / drug effects
Vasopressins / pharmacology
Water-Electrolyte Balance*
Reg. No./Substance:
0/Enzyme Inhibitors; 11000-17-2/Vasopressins; 11128-99-7/Angiotensin II; 52-39-1/Aldosterone; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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