Document Detail

Electrolyte output, blood pressure, and family history of hypertension.
MedLine Citation:
PMID:  433826     Owner:  NLM     Status:  MEDLINE    
Adult, normotensive subjects were divided into two groups on the basis of whether their first degree relatives were diagnosed as being hypertensive. Urine samples were collected over a 24-hr period for 3 days and analyzed for electrolyte excretion; the rate of electrolyte excretion was also measured separately during the overnight period. Significant correlations were shown between blood pressure and sodium and chloride excretion, both the 24-hr total and the overnight rate; Na/K ratio; weight; and body mass index for those subjects with a positive family history of hypertension. In subjects with no family history of hypertension there were no significant correlations between those parameters and blood pressure. The rate of urinary excretion of sodium overnight may provide a means for further studies on populations to determine the interrelationship between sodium excretion, other parameters, blood pressure, and family history of hypertension.
P I Pietinen; O Wong; A M Altschul
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  32     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-06-29     Completed Date:  1979-06-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  997-1005     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure*
Body Constitution
Body Weight
Chlorides / metabolism*
Hypertension / genetics,  metabolism,  physiopathology*
Obesity / physiopathology
Potassium / metabolism*
Sodium / metabolism*
Reg. No./Substance:
0/Chlorides; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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