Document Detail

Electrolyte disturbances and abnormal urine analysis in children with dengue infection.
MedLine Citation:
PMID:  20578484     Owner:  NLM     Status:  MEDLINE    
Serum electrolytes and urine analysis results were retrospectively reviewed in children with either dengue fever (DF) or dengue hemorrhagic fever (DHF). Children who had positive serology for dengue infection and serum electrolytes determined before starting intravenous fluid were included in the study. During the years 2004-2007, 73 DF patients, age 9.29 +/- 3.62 years, and 77 DHF patients, age 10.04 +/- 3.64 years were enrolled in the study. The patients were admitted to the hospital on average on days 4.12 +/- 1.1 and 4.25 +/- 1.4 of febrile illness for DF and DHF, respectively. The prevalence of hyponatremia in patients with DF was 61% and DHF was 72% (p = 0.149). The mean serum sodium levels in patients with DF and DHF were 133.5 +/- 3.52 and 133.5 +/- 3.20 mEq/l (p = 0.938), respectively. The prevalence of hyponatremia in patients with mild (grade I), moderate (grade II) and severe (grade III-IV) DHF were 70, 77, and 78% (p = 0.729), respectively, and the mean serum sodium levels were 134.1 +/- 3.05, 132.9 +/- 3.33, and 132.5 +/- 3.28 (p = 0.189), respectively. The prevalence of hypokalemia in patients with DF was 14% and 17% in patients with DHF (p = 0.588). A high urine specific gravity reflecting dehydration was found in 63% of patients with DF and 60% of patients with DHF (p = 0.77). The prevalences of hematuria in patients with DF and DHF were 18% and 27% (p = 0.182), respectively and proteinuria were 15% and 27% (p = 0.072), respectively. The prevalences of hematuria and proteinuria were not different among patients with mild, moderate and severe DHF. No patients had gross hematuria or developed acute renal failure requiring dialysis. Mild hyponatremia is a common electrolyte disturbance and renal involvement is mild in patients with DF and DHF.
Adisorn Lumpaopong; Pinyada Kaewplang; Veerachai Watanaveeradej; Prapaipim Thirakhupt; Sangkae Chamnanvanakij; Konggrapun Srisuwan; Natthida Pongwilairat; Yupapin Chulamokha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Southeast Asian journal of tropical medicine and public health     Volume:  41     ISSN:  0125-1562     ISO Abbreviation:  Southeast Asian J. Trop. Med. Public Health     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-06-28     Completed Date:  2010-07-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0266303     Medline TA:  Southeast Asian J Trop Med Public Health     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  72-6     Citation Subset:  IM    
Division of Pediatric Nephrology, Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand.
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MeSH Terms
Dengue / blood*,  complications,  urine*
Dengue Hemorrhagic Fever / blood,  complications,  urine
Hematuria / blood,  etiology,  urine
Hypokalemia / blood,  etiology,  urine
Hyponatremia / blood,  etiology,  urine
Proteinuria / blood,  etiology,  urine
Retrospective Studies
Water-Electrolyte Imbalance / blood*,  etiology,  urine*

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