Document Detail


Electrographic high-frequency activity and epilepsy.
MedLine Citation:
PMID:  20031373     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High-frequency electrographic activity (HFA) has a frequency of 80-600Hz. It can be observed interictally in epileptic foci and also at the onset of epileptic seizures. There are several hypotheses about how HFA is generated, and it has been suggested that the underlying mechanisms may play an important role in epileptogenesis and ictogenesis. The high specificity of HFA for epileptic foci is now used during presurgical evaluation to help localize epileptic focus. In this article we review the current state of knowledge regarding this phenomenon and challenges for the future studies focusing on HFA.
Authors:
Premysl Jiruska; Andrew D Powell; Wei-Chih Chang; John G R Jefferys
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-12-23
Journal Detail:
Title:  Epilepsy research     Volume:  89     ISSN:  1872-6844     ISO Abbreviation:  Epilepsy Res.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703089     Medline TA:  Epilepsy Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  60-5     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier B.V. All rights reserved.
Affiliation:
Neuroscience, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Brain Mapping
Cerebral Cortex / physiopathology*
Electroencephalography
Epilepsy / physiopathology*
Humans
Seizures / physiopathology*

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