Document Detail


Electroencephalography as a diagnostic instrument in Alzheimer's disease: reviews and perspectives.
MedLine Citation:
PMID:  9447445     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electroencephalography is the only diagnostic instrument directly reflecting cortical neuronal functioning, and it remains an important clinical tool in the diagnosis and differential diagnosis of Alzheimer's disease (AD). Although a normal EEG is found in many patients with mild AD, a pathological EEG is an important finding, because such a result is not in line with differential diagnoses such as depression or pseudodementia within a dissociative disorder. The vast majority of patients with moderate to severe AD have a pathological EEG. A normal EEG in this patient group is more in line with subcortical dementia or frontal lobe degeneration than with AD. Compared to SPECT or routine structural brain imaging (cCT, MRT), EEG has a comparable diagnosis sensitivity and a higher specificity. For monitoring changes of brain function by serial recordings (e.g., during therapy with antidementia drugs), EEG is the best available method.
Authors:
U Hegerl; H J Möller
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International psychogeriatrics / IPA     Volume:  9 Suppl 1     ISSN:  1041-6102     ISO Abbreviation:  Int Psychogeriatr     Publication Date:  1997  
Date Detail:
Created Date:  1998-04-15     Completed Date:  1998-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007918     Medline TA:  Int Psychogeriatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  237-46; discussion 247-52     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Ludwig-Maximilians-Universität München, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alzheimer Disease / diagnosis*
Diagnosis, Differential
Electroencephalography*
Event-Related Potentials, P300
Humans
Magnetic Resonance Imaging
Severity of Illness Index
Sleep, REM
Tomography, Emission-Computed
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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