| Electrocochleographic effects of ear canal pressure change in subjects with Menière's disease. | |
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MedLine Citation:
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PMID: 8915416 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the relationship between objective changes in electrocochleographic (ECochG) parameters and subjective changes in symptoms in a group of patients with Menière's disease/endolymphatic hydrops (MD/ELH) after application of positive and negative atmospheric pressure changes to the sealed ear canal. Our goals were to further examine the therapeutic effects of atmospheric pressure change on the treatment of MD/ELH, as reported by a series of Swedish studies, and to examine the utility of ECochG for monitoring these effects. By combining a clinical immittance unit and an evoked potential unit, ECochG responses were obtained from the tympanic membrane while different atmospheric pressures were applied indirectly to the middle ear via the external ear canal. For comparison, ECochG responses at various atmospheric pressures also were obtained for otologically normal subjects. For the MD/ELH group, there was a significant (p < 0.01) reduction in the abnormal summating potential/action potential (SP/AP) amplitude ratio, although the amplitude ratios did not become "normal." There was no significant effect of ear canal pressure change on ECochG components for the normative subjects. Although these findings were encouraging regarding the therapeutic effects of overpressure, they were not accompanied with changes in MD/ELH symptoms. |
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Authors:
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R F Storms; J A Ferraro; B S Thedinger |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The American journal of otology Volume: 17 ISSN: 0192-9763 ISO Abbreviation: Am J Otol Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1997-03-18 Completed Date: 1997-03-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7909513 Medline TA: Am J Otol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 874-82 Citation Subset: IM |
Affiliation:
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Hearing and Speech Department, University of Kansas Medical Center, Kansas City, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Atmospheric Pressure* Audiometry, Evoked Response* Audiometry, Pure-Tone Ear, External / physiology* Endolymphatic Hydrops / physiopathology Female Hearing Loss, Sensorineural / complications, diagnosis Humans Male Meniere Disease / diagnosis*, physiopathology Middle Aged Random Allocation Reflex, Acoustic Tympanic Membrane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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