| Electroclinical features of idiopathic generalised epilepsy with persisting absences in adult life. | |
| | |
MedLine Citation:
|
PMID: 8937341 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To describe the electroclinical features of typical absences persisting in adult life. METHODS: Twelve adult patients (aged 21 to 56 years) with idiopathic generalised epilepsy featuring typical absences as the prominent clinical feature were studied. All patients underwent a full clinical and neurophysiological investigation including ictal documentation of seizures. RESULTS: Neurological examination and neuroradiological investigations were normal in all cases. Clinical findings included a median age at onset of absences of 14 (range 4-32) years, almost constant tonic-clonic seizures (in 83% of patients), frequent episodes of absence status (in 33% of patients), and associated cognitive or psychiatric disturbances. Interictal EEG findings showed normal background activity, generalised paroxysms of spike waves or polyspike waves, and inconstant focal spikes (in five patients); runs of polyspikes were seen during non-REM sleep. Ictal EEG findings showed generalised spike waves at 3 Hz, sometimes preceded by multiple spikes, or more complex EEG patterns with sequences of polyspikes intermingled with spike waves or polyspike waves, showing discharge fragmentation or variation of intradischarge frequency. CONCLUSION: The results of the present study show that absences persisting in adult life may show particular clinical and EEG patterns, distinct from those in childhood or adolescence. |
| | |
Authors:
|
R Michelucci; G Rubboli; D Passarelli; P Riguzzi; L Volpi; L Parmeggiani; R Rizzi; E Gardella; C A Tassinari |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of neurology, neurosurgery, and psychiatry Volume: 61 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 1996 Nov |
Date Detail:
|
Created Date: 1996-12-20 Completed Date: 1996-12-20 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 471-7 Citation Subset: IM |
Affiliation:
|
Department of Neurology, University of Bologna, Bellaria Hospital, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Age of Onset Electrocardiography Electroencephalography Electromyography Epilepsy, Generalized / diagnosis, physiopathology* Female Humans Male Middle Aged |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relations between genotype and phenotype in German patients with the Machado-Joseph disease mutation...
Next Document: Cognitive impairment after acute encephalitis: comparison of herpes simplex and other aetiologies.