Document Detail


Electrochemical quantification of reactive oxygen and nitrogen: challenges and opportunities.
MedLine Citation:
PMID:  19280182     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a crucial role in chemical signaling processes of biological cells. Electrochemistry is one of the rare methods able to directly detect these species. ROS and RNS can be monitored in the local microenvironment of cells in real time at the site where the actual signaling takes place. This review presents recent advances made with amperometric electrochemical techniques. Existing challenges for the quantification of ROS and RNS in biological systems are discussed to promote the development of innovative and reliable cell-based assays.
Authors:
Sabine Borgmann
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-03-12
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  394     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-09     Completed Date:  2009-07-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  95-105     Citation Subset:  IM    
Affiliation:
Biologisch-Chemische Mikrostrukturtechnik, Fakultät Chemie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany. sabine.borgmann@tu-dortmund.de
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MeSH Terms
Descriptor/Qualifier:
Electrochemistry / methods*
Reactive Nitrogen Species / analysis*
Reactive Oxygen Species / analysis*
Chemical
Reg. No./Substance:
0/Reactive Nitrogen Species; 0/Reactive Oxygen Species

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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