Document Detail

Electrocardiographically and symptomatically silent myocardial ischemia during exercise testing.
MedLine Citation:
PMID:  1942490     Owner:  NLM     Status:  MEDLINE    
Certain patients with coronary artery disease (CAD) may have neither ST depression nor chest pain during exercise despite the presence of myocardial ischemia. The frequency and characteristics of such electrocardiographically and symptomatically silent ischemia were studied in 171 patients with both angiographically documented CAD and scintigraphically documented ischemia. Fifty-six (33%) of 171 patients had neither ST depression nor chest pain (Group N), and 115 (67%) had ST depression and/or chest pain (Group P). The two groups were similar with respect to age, gender, the prevalence of prior infarction, and peak systolic blood pressure. Group N patients, however, had a higher mean peak heart rate and rate-pressure product, less severe scintigraphic ischemia, a lower lung thallium-201 uptake, and a smaller number of diseased vessels. Stepwise discriminant analysis showed a history of effort angina, lung thallium-201 uptake, and scintigraphic severity of ischemia to be significant discriminators between Groups N and P. In conclusion, electrocardiographically and symptomatically silent ischemia may be common during exercise in patients with CAD, and less severe ischemia may be one of important determinants.
C Kurata; K Tawarahara; K Sakata; T Taguchi; Y Fukumoto; A Kobayashi; N Yamazaki; H Tanaka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  55     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-12-06     Completed Date:  1991-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  825-34     Citation Subset:  IM    
Third Department of Internal Medicine, Hamamatsu University School of Medicine, Japan.
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MeSH Terms
Coronary Angiography
Coronary Disease / diagnosis,  physiopathology*
Exercise Test*
Heart / radionuclide imaging
Middle Aged
Thallium Radioisotopes / diagnostic use
Reg. No./Substance:
0/Thallium Radioisotopes

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