Document Detail

Electrocardiographic waveform analysis for predicting the success of defibrillation.
MedLine Citation:
PMID:  11098949     Owner:  NLM     Status:  MEDLINE    
A new electrocardiographic predictor of the likelihood that an electrical shock would restore a perfusing rhythm is described. The intent was to develop a prognosticator that would be displayed during precordial compression. We anticipated that such a predictor would allow more selective timing of electrical shocks and reduce electrical injury to the myocardium caused by repetitive shocks. In a porcine model of cardiac arrest because of ventricular fibrillation, electrocardiographic recordings of ventricular fibrillation wavelets were analyzed and transformed into an amplitude spectrum area (AMSA). An AMSA value of 21 mV x Hz predicted restoration of perfusing rhythm with a positive predictive value equivalent to that of coronary perfusion pressure. More important, the negative predictive value that a shock would fail to reestablish spontaneous circulation was 96%. AMSA, therefore, has the potential for guiding optimal timing of defibrillation.
H P Povoas; J Bisera
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  28     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-01     Completed Date:  2000-12-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  N210-1     Citation Subset:  AIM; IM    
Institute of Critical Care Medicine, Palm Springs, CA , USA.
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MeSH Terms
Electric Countershock / methods*
Fourier Analysis*
Logistic Models
Models, Cardiovascular
Predictive Value of Tests
Therapy, Computer-Assisted*
Ventricular Fibrillation / diagnosis,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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