Document Detail

Electrocardiographic strain and endomyocardial radial strain in hypertensive patients.
MedLine Citation:
PMID:  20510470     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Electrocardiographic strain pattern (ECGS) is a well-recognized marker of the presence and severity of anatomic left ventricular hypertrophy (LVH) and also has been associated with adverse prognosis in hypertensive patients. Left ventricular (LV) endomyocardial radial strain (Endo-RS) is predominant in systolic LV wall thickening compared with epimyocardial radial strain (Epi-RS) in a normal heart. However, it remains unclear whether the ratio of Endo-RS to Epi-RS alters in hypertensive patients, especially in those with ECGS.
METHODS: Endo-RS and Epi-RS in 9 non-hypertensive subjects (Group A), 26 hypertensive subjects without ECGS (Group B), and 16 hypertensive subjects with ECGS (Group C) were assessed by a tissue tracking system.
RESULTS: Relative wall thickness, LV mass index, and voltage of SV1+RV5 were significantly greater in Group C than in both Groups A and B. Although no significant difference was seen in Epi-RS among the 3 groups, Endo-RS and the ratio of Endo-RS to Epi-RS (Endo/Epi-RS) in Group C were significantly lower than those in the other two groups. Multiple logistic regression analysis revealed that the only factor which significantly correlated with Endo/Epi-RS in the first tertile (<1.6) was the presence of ECGS (OR=9.28, p=0.01).
CONCLUSIONS: The appearance of ECGS significantly correlated with not only the development of LV hypertrophy but also with the attenuation of Endo-RS.
Nobuo Nakamura; Kumiko Hirata; Toshio Imanishi; Akio Kuroi; Yu Arita; Hideyuki Ikejima; Hiroto Tsujioka; Kazushi Takemoto; Takashi Tanimoto; Hironori Kitabata; Shigeho Takarada; Takashi Kubo; Masato Mizukoshi; Atsushi Tanaka; Mikio Arita; Takashi Akasaka
Publication Detail:
Type:  Journal Article     Date:  2010-05-26
Journal Detail:
Title:  International journal of cardiology     Volume:  150     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  319-24     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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