Document Detail


Electrocardiographic prediction of the severity of posterior wall perfusion defects on rest technetium-99m Sestamibi myocardial perfusion imaging.
MedLine Citation:
PMID:  16003699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To identify electrocardiogram (ECG) variables predicting the severity of previous posterior wall myocardial infarction as measured by technetium-99m-Sestamibi rest single-photon emission computed tomography, we assessed agreement between ECG criteria and posterior wall perfusion defects (PWPDs) in 236 patients. Established ECG criteria for posterior and posterolateral infarctions were present in 22% and 19% of patients, respectively, and did not predict severity of PWPD ( P = NS). Univariate predictors of severity were the Selvester QRS score (SQS) ( P = .001) and an upright T wave in V 1 (UTV 1 ) greater than 0.2 mV ( P = .001). Regression analysis demonstrated that SQS ( P = .0001) and UTV 1 greater than 0.2 mV ( P = .006) were highly predictive of severity ( c statistic = 0.793). All severe PWPDs had an SQS of 2 or higher. Established ECG patterns for diagnosis of posterior infarction are insensitive and poor predictors of severity. The SQS and UTV 1 are effective for the diagnosis of posterior infarction and useful for the estimation of infarct severity.
Authors:
Radu Petrovici; Louise Emmett; Douglas S Lee; Mansoor Husain; Robert M Iwanochko
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  38     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-07-08     Completed Date:  2005-11-10     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  195-203     Citation Subset:  IM    
Affiliation:
Robert J. Burns Nuclear Cardiology Laboratory, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8.
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MeSH Terms
Descriptor/Qualifier:
Coronary Circulation / physiology
Electrocardiography / classification*,  statistics & numerical data
Female
Forecasting
Gated Blood-Pool Imaging
Heart Ventricles / radionuclide imaging*
Humans
Male
Middle Aged
Myocardial Infarction / diagnosis*,  physiopathology,  radionuclide imaging
Predictive Value of Tests
Radiopharmaceuticals / diagnostic use*
Rest / physiology
Retrospective Studies
Sensitivity and Specificity
Technetium Tc 99m Sestamibi / diagnostic use*
Tomography, Emission-Computed, Single-Photon*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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