Document Detail

Electrocardiographic patterns in acute inferior myocardial infarction with and without right ventricle involvement: classification, diagnostic and prognostic value, masking effect.
MedLine Citation:
PMID:  9929754     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In acute inferior myocardial infarction (AIMI), the ST depression from V1 to V4 has been the subject of many papers, while the ST changes in other leads, their association, and the right ventricular (RV) involvement have been studied less. HYPOTHESIS: This study was performed to contribute to the meaning of the ST changes and RV involvement in AIMI. METHODS: Seventy-one patients, admitted within 6 h from symptom onset, all thrombolysed, were enrolled. We classified them according to ST patterns and RV involvement. We divided the right coronary artery into three segments, considering the origin of RV branch and the crux as dividing points. We established a coronary score attributing 2 points to each terminal branch. Comparisons were performed between the electrocardiographic (ECG) findings at onset, the creatine phosphokinase (CPK) peaks, the radionuclide ejection fractions, and the coronary angiographies. RESULTS: We found that the ST changes give indications regarding the site, extension, and extent of AIMI; RV involvement can mask posterior extension, points to the right coronary as the culprit vessel (100%), and, with high probability, indicates the proximal segment as the site of the lesion; the ECG signs of isolated AIMI indicate a peripheral obstruction; and a collateral circulation may appear relatively early. CONCLUSIONS: Our findings prove the diagnostic and prognostic value of the ST changes and RV involvement at the onset of AIMI and suggest that the higher in-hospital mortality and complication rates found with RV involvement and reported in the literature are related more to posterior extension, masked by RV involvement than to this involvement per se. Furthermore, these findings prove the clinical value of our classification of the AIMIs and distinction in segments of the right coronary artery.
E Correale; R Battista; A Martone; F Pietropaolo; V Ricciardiello; D DiGirolamo; S Barlera; A P Maggioni
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  22     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-04-01     Completed Date:  1999-04-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-44     Citation Subset:  IM    
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
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MeSH Terms
Coronary Angiography
Coronary Care Units
Creatine Kinase / blood
Diagnosis, Differential
Electrocardiography* / classification
Follow-Up Studies
Heart Catheterization
Heart Ventricles / physiopathology*,  radiography,  radionuclide imaging
Myocardial Infarction / classification,  diagnosis,  enzymology,  physiopathology*
Prospective Studies
Radionuclide Ventriculography
Stroke Volume
Reg. No./Substance:
EC Kinase

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