| Electrocardiographic gated (99m)Tc-MIBI SPECT for functional assessment of patients after coronary artery bypass surgery: comparison of wall thickening and wall motion analysis. | |
| | |
MedLine Citation:
|
PMID: 11994519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Abnormal septal motion after coronary artery bypass graft surgery (CABG) is a common finding. This study was undertaken to investigate the change in various global and regional ventricular function parameters measured by gated myocardial perfusion SPECT after surgery and to determine which quantitative parameter of WT and WM is more appropriate for the evaluation of regional cardiac function, especially in the septum of patients with CABG. METHODS: Before and 3 to 5 wk after CABG (all patients underwent at least 1 bypass grafting to the left anterior descending coronary artery), 35 patients (28 men, 7 women) underwent gated SPECT using (99m)Tc-methoxyisobutylisonitrile. Quantitative global and regional ventricular functional analysis was performed using quantitative gated SPECT software. RESULTS: Global ejection fraction did not change (59.3% +/- 16.0% to 60.5% +/- 14.5%, P = 0.24). However, end-diastolic and end-systolic volumes lessened significantly after CABG (81.4 +/- 37.3 mL to 68.9 +/- 28.9 mL, P < 0.0001, and 38.1 +/- 33.1 mL to 30.4 +/- 23.0 mL, P < 0.005, respectively). As global function parameters, the changes in both total WM (r = 0.88) and WT (r = 0.86) correlated well with the change in ejection fraction after surgery. Segmental analysis showed a significant postoperative increase in relative tracer uptake in the anterior, anteroseptal, inferoseptal, and inferior walls and in the apex. Segmental wall motion (WM) deteriorated in the anteroseptal, inferoseptal, and mid anterior walls. On the other hand, anterolateral, inferolateral, and inferior WM increased. As a whole, these WM changes showed a reduction in septal motion associated with a concomitant increase in lateral motion after surgery. Segmental wall thickening, however, did not decrease in septal areas and did not increase in the lateral wall and correlated with percentage tracer uptake (r = 0.69) better than WM did (r = 0.30) after CABG. CONCLUSION: In patients with CABG, postoperative WM analysis by gated SPECT underestimated septal motion and overestimated lateral motion because of exaggerated systolic anteromedial cardiac translation. Therefore, wall thickening analysis would be recommended for the evaluation of postoperative cardiac function. |
| | |
Authors:
|
Junichi Taki; Takahiro Higuchi; Kenichi Nakajima; Ichiro Matsunari; Eui-Hyo Hwang; Hisashi Bunko; Michio Kawasuji; Go Watanabe; Norihisa Tonami |
Related Documents
:
|
8886239 - Regional three-dimensional geometry of the normal human left ventricle using cine compu... 829509 - Ultrasonic identification and examination of fetal heart structures. 8249839 - Comparison of the usefulness of the implantable cardioverter-defibrillator and subendoc... 18930629 - Ultrasonic strain versus coronary flow velocity pattern for predicting regional wall mo... 19329419 - Cardiac magnetic resonance detection and typical appearance of microvascular obstructio... 14578599 - Early detection of doxorubicin-induced myocardial damage by ultrasound tissue character... 6412599 - Chronic heart failure in the elderly: vasodilator therapy. 23601059 - Coronary artery anatomy in congenital heart disease. 11514989 - Early clinical experience with the 6 french angio-seal device: immediate closure of fem... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 43 ISSN: 0161-5505 ISO Abbreviation: J. Nucl. Med. Publication Date: 2002 May |
Date Detail:
|
Created Date: 2002-05-07 Completed Date: 2002-05-23 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: United States |
Other Details:
|
Languages: eng Pagination: 589-95 Citation Subset: IM |
Affiliation:
|
Department of Biotracer Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan. taki@med.kanazawa-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Coronary Artery Bypass* Electrocardiography* Female Heart / physiopathology*, radionuclide imaging* Humans Male Middle Aged Technetium Tc 99m Sestamibi / diagnostic use* Tomography, Emission-Computed, Single-Photon* Ventricular Function |
| Chemical | |
Reg. No./Substance:
|
109581-73-9/Technetium Tc 99m Sestamibi |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Kidney allografts and remaining contralateral donor kidneys before and after transplantation: assess...
Next Document: Potential of (99m)Tc-MIBI for detecting bone marrow metastases.