Document Detail


Electrocardiographic changes and myocarditis in trichinellosis: a retrospective study of 154 patients.
MedLine Citation:
PMID:  15949188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The frequencies of electrocardiographic (ECG) abnormalities and myocarditis were determined, retrospectively, among 154 cases of trichinellosis [101 males and 53 females, with a mean (S.D.) age of 35.60 (14.64) years] who were hospitalized at the University Hospital for Infectious Diseases in Zagreb, Croatia, over a 5-year period. Eighty-seven (56%) of the patients, most of them in the invasive phase of infection with Trichinella spiralis, were found to have abnormalities when examined by 12-lead, resting electrocardiography. The ECG disorder most frequently observed was a non-specific ventricular repolarization disturbance (with ST-T wave changes), followed by bundle-branch conduction disturbances, and sinus tachycardia. The other ECG disorders recorded, during various phases of the infection, were sinus bradycardia, right bundle-branch block, supraventricular and ventricular extrasystoles, low-voltage QRS complexes in standard limb leads, first-degree atrio-ventricular block, and atrial fibrillation. Eighteen (12%) of the patients were identified as cases of myocarditis (13 in the invasive phase and five in the convalescent) and two (1.3%) as cases of myopericarditis. One patient developed acute myocardial infarction 28 days after the onset of disease and died soon thereafter; an autopsy revealed multiple necroses and fibroses of the myocardium and thrombus of a coronary artery. Although ECG abnormalities appear to be a common feature of trichinellosis, especially during the invasive phase of the disease, they are rarely associated with a poor prognosis. A transient, non-specific, ventricular-repolarization disturbance is the abnormality most commonly observed.
Authors:
I Puljiz; A Beus; I Kuzman; S Seiwerth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of tropical medicine and parasitology     Volume:  99     ISSN:  0003-4983     ISO Abbreviation:  Ann Trop Med Parasitol     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-13     Completed Date:  2005-09-01     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  2985178R     Medline TA:  Ann Trop Med Parasitol     Country:  England    
Other Details:
Languages:  eng     Pagination:  403-11     Citation Subset:  IM    
Affiliation:
University Hospital for Infectious Diseases Dr Fran Mihaljević, Zagreb, Croatia. ipuljiz@bfm.hr
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Coronary Vessels / pathology
Electrocardiography
Female
Humans
Male
Middle Aged
Myocardial Infarction / parasitology,  pathology
Myocarditis / parasitology*,  pathology,  physiopathology
Prognosis
Retrospective Studies
Trichinellosis / pathology,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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