| Electrocardiographic changes in cardiomyopathic Syrian hamsters (strain BIO 8262). | |
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MedLine Citation:
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PMID: 143276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Under ether anesthesia electrocardiograms were derived from Syrian hamsters (strain BIO 8262) suffering from cardiomyopathy and muscular dystrophy. In addition, ventricular weights and body weight were determined. Young hamsters -- not yet showing morphological signs of the cardiomyopathy with the exception of possible left ventricular hypertrophy -- demonstrated only a longer ventricular activation time than normal hamsters. With the onset of cardiac necrotization left axis deviation in frontal plane projection and right bundle branch blocks are developing in the cardiomyopathic hamsters followed by first degree atrioventricular conduction defects. During the late stage of the cardiomyopathy left bundle branch blocks are additionally arising, while left ventricular hypertrophy is disappearing. Since no overt heart failure is occurring in this strain of cardiomyopathic hamsters, gradual development of high degree conduction defects is assumed to terminate their lives. The electrocardiographic pattern of the hamster cardiomyopathy fits partly into that of human primary as well as secondary cardiomyopathy. Nevertheless, it seems to form an entity of its own, as arrhythmias, higher degree atrioventricular conduction disturbances, typical signs of ventricular or septal hypertrophy, abnormal P and Q waves, ST segment and T wave changes are lacking. |
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Authors:
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K Lossnitzer; N Grewe; A Konrad; J Adler |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Basic research in cardiology Volume: 72 ISSN: 0300-8428 ISO Abbreviation: Basic Res. Cardiol. Publication Date: 1977 Jul-Aug |
Date Detail:
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Created Date: 1977-10-31 Completed Date: 1977-10-31 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0360342 Medline TA: Basic Res Cardiol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 421-35 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight Bundle-Branch Block / diagnosis Cardiomegaly / diagnosis Cardiomyopathies / diagnosis, veterinary* Cricetinae* Electrocardiography Female Male Mesocricetus* Muscular Dystrophy, Animal / diagnosis Myocardium / pathology Organ Size Rodent Diseases / diagnosis* |
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