Document Detail


Electrocardiographic changes during prolonged coronary artery occlusion in man: comparison of standard and high-frequency recordings.
MedLine Citation:
PMID:  9649905     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Detection of acute myocardial ischaemia using electrocardiographic methods is generally based on assessment of the ST segments in the standard 12-lead electrocardiogram (ECG). Several studies have also shown changes in high-frequency QRS components during acute ischaemia. The purpose of the present study was to determine the changes in high-frequency QRS components during prolonged percutaneous transluminal coronary angioplasty (PTCA) and to compare these changes with ST-segment deviations in the standard 12-lead ECG. The study population consisted of 19 patients receiving prolonged PTCA. Standard and high-resolution signal-averaged ECGs were recorded before and during balloon inflation. The high-resolution recordings were performed using bipolar X, Y and Z leads. The QRS complexes in the high-resolution signal-averaged ECGs were analysed within a bandwidth of 150-250 Hz. During inflation, significant reductions in high-frequency QRS components were observed (12-72%). Changes in the high-frequency QRS components were seen in four of the patients without ST-segments deviation in the standard ECG. The correlation between the ST-segment deviation and the reduction in high-frequency QRS components was weak (r = 0.27). Acute coronary artery occlusion produces changes in high-frequency QRS components, even in the absence of ST-segment deviation in the standard ECG. Further studies need to be carried out to evaluate whether analysis of high-frequency QRS components could provide a method for detecting myocardial ischaemia and give additional information to that available in the ST segment in the standard ECG.
Authors:
J Pettersson; P Lander; O Pahlm; L Sörnmo; S G Warren; G S Wagner
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  18     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-09-18     Completed Date:  1998-09-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  179-86     Citation Subset:  IM    
Affiliation:
Department of Clinical Physiology, Lund University, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angioplasty, Transluminal, Percutaneous Coronary
Electrocardiography / classification*,  methods*
Female
Humans
Male
Middle Aged
Myocardial Ischemia / diagnosis*,  therapy
Signal Processing, Computer-Assisted
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