Document Detail


Electrical remodeling in ischemia and infarction.
MedLine Citation:
PMID:  10533567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a review of the electrophysiologic changes occurring at different times following myocardial infarction, both in the infarcted region (substrate) and in areas remote from the infarct. Regulators of channel function which might contribute to re-modeling, including autocrine/paracrine factors involved in ion channel gene regulation, are discussed.
Authors:
J M Pinto; P A Boyden
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Cardiovascular research     Volume:  42     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-11-04     Completed Date:  1999-11-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  284-97     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Columbia College of Physicians and Surgeons, New York, NY 10032, USA.
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MeSH Terms
Descriptor/Qualifier:
Action Potentials*
Animals
Biological Transport, Active*
Cardiomegaly / metabolism,  physiopathology
Dogs
Gene Expression Regulation
Guinea Pigs
Humans
Ion Channels / metabolism,  pharmacology,  physiology*
Ion Transport
Myocardial Infarction / metabolism,  physiopathology*
Myocardial Ischemia / metabolism,  physiopathology*
Myocardium / metabolism,  pathology
Rats
Sarcolemma / genetics,  metabolism
Time Factors
Transcription, Genetic
Grant Support
ID/Acronym/Agency:
HL-30557/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Ion Channels

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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