Document Detail


Electrical and mechanical response in biventricular mechanical alternans.
MedLine Citation:
PMID:  92266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mechanical alternans of various degrees is produced by rapid heart rates, slower rates in failing hearts and can be brought about by a single extra systole. It has also been shown that the two ventricles may exhibit different degrees of mechanical alternation. The present study was planned to clarify the possible mechanism inducing this latter phenomenon. For this reason myocardial tension was recorded simultaneously from the two ventricles as well as through a miniature strain gage capable of measuring electrogram and myocardial tension of a small area -- just adjacent to a stimulating electrode. The heart was driven at a steady heart rate through one electrode and very late premature beats were applied at various coupling times at another site through an electrode attached to the miniature strain gage. It was found that the degree of mechanical alternans is markedly different at the sites of measurements in either ventricle. These changes could be related to the time interval elapsed between the application of the electrical stimulus and the occurrence of the mechanical response.
Authors:
Y Hasin; O Sarel; S Rogel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives internationales de physiologie et de biochimie     Volume:  87     ISSN:  0003-9799     ISO Abbreviation:  Arch. Int. Physiol. Biochim.     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1980-01-24     Completed Date:  1980-01-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0405355     Medline TA:  Arch Int Physiol Biochim     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  19-28     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure
Dogs
Electric Stimulation
Heart / physiology*
Heart Rate*
Physical Stimulation
Ventricular Function

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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