| Electrical coupling between embryonic cells by way of extracellular space and specialized junctions. | |
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MedLine Citation:
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PMID: 5415239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The meroblastic egg of the teleost, Fundulus heteroclitus, was studied electrophysiologically from cleavage to mid-gastrula stages. The yolk is an intracellular inclusion surrounded by a membrane of high resistivity (50 k ohmcm(2)). This membrane generates a cytoplasm-negative resting potential in later stages. Cells of all stages studied are coupled electrically. In gastrulae, coupling is both by way of specialized junctions between cells and by way of intra-embryonic extracellular space, the segmentation cavity. The latter mode is present because the segmentation cavity is sealed off from the exterior by a high resistance barrier, and the outer membrane of surface cells is of high resistance (50-100 k ohmcm(2)) compared to the inner membrane. It can be inferred that clefts between surface cells are occluded by circumferential junctions. Isolated cells from late cleavage stages develop coupling in vitro, confirming the existence of coupling by way of intercellular junctions. Both modes of coupling could mediate communication between cells that is important in embryonic development. |
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Authors:
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M V Bennett; J P Trinkaus |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of cell biology Volume: 44 ISSN: 0021-9525 ISO Abbreviation: J. Cell Biol. Publication Date: 1970 Mar |
Date Detail:
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Created Date: 1970-04-03 Completed Date: 1970-04-03 Revised Date: 2010-09-13 |
Medline Journal Info:
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Nlm Unique ID: 0375356 Medline TA: J Cell Biol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 592-610 Citation Subset: IM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Transport, Active Cell Membrane Permeability* Cytoplasm Electron Transport Electrophysiology* Embryo, Nonmammalian / cytology* Fishes / embryology Membrane Potentials* Models, Biological |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Cell Biol ISSN: 0021-9525 ISSN: 1540-8140 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © 1970 by The Rockefeller University Press Received Day: 12 Month: 8 Year: 1969 Revision Received Day: 15 Month: 10 Year: 1969 Print publication date: Day: 1 Month: 3 Year: 1970 Volume: 44 Issue: 3 First Page: 592 Last Page: 610 ID: 2107981 PubMed Id: 5415239 |
| ELECTRICAL COUPLING BETWEEN EMBRYONIC CELLS BY WAY OF EXTRACELLULAR SPACE AND SPECIALIZED JUNCTIONS | |
| M. V. L. Bennett | |
| J. P. Trinkaus | |
| From the Department of Anatomy, Albert Einstein College of Medicine, New York, New York 10461, the Department of Biology, Yale University, New Haven, Connecticut 06520, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543 |
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