Document Detail

Electrical coupling between embryonic cells by way of extracellular space and specialized junctions.
Jump to Full Text
MedLine Citation:
PMID:  5415239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The meroblastic egg of the teleost, Fundulus heteroclitus, was studied electrophysiologically from cleavage to mid-gastrula stages. The yolk is an intracellular inclusion surrounded by a membrane of high resistivity (50 k ohmcm(2)). This membrane generates a cytoplasm-negative resting potential in later stages. Cells of all stages studied are coupled electrically. In gastrulae, coupling is both by way of specialized junctions between cells and by way of intra-embryonic extracellular space, the segmentation cavity. The latter mode is present because the segmentation cavity is sealed off from the exterior by a high resistance barrier, and the outer membrane of surface cells is of high resistance (50-100 k ohmcm(2)) compared to the inner membrane. It can be inferred that clefts between surface cells are occluded by circumferential junctions. Isolated cells from late cleavage stages develop coupling in vitro, confirming the existence of coupling by way of intercellular junctions. Both modes of coupling could mediate communication between cells that is important in embryonic development.
Authors:
M V Bennett; J P Trinkaus
Related Documents :
1510249 - Communication compartments in the axial mesoderm of the chick embryo.
12045219 - Involvement of asip/par-3 in the promotion of epithelial tight junction formation.
18989439 - Silicon microchips for manipulating cell-cell interaction.
19593789 - Profilin-1 overexpression restores adherens junctions in mda-mb-231 breast cancer cells...
18570249 - Two different mechanisms of planar cell intercalation leading to tissue elongation.
8977159 - Gap junction involvement in secretion: the pancreas experience.
1690169 - Glycoprotein hormone alpha subunit in endocrine cells of human oxyntic mucosa. studies ...
9619099 - Uncoupling growth from the cell cycle.
22465479 - Neurotrophins and cell death.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of cell biology     Volume:  44     ISSN:  0021-9525     ISO Abbreviation:  J. Cell Biol.     Publication Date:  1970 Mar 
Date Detail:
Created Date:  1970-04-03     Completed Date:  1970-04-03     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  0375356     Medline TA:  J Cell Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-610     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport, Active
Cell Membrane Permeability*
Cytoplasm
Electron Transport
Electrophysiology*
Embryo, Nonmammalian / cytology*
Fishes / embryology
Membrane Potentials*
Models, Biological
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Cell Biol
ISSN: 0021-9525
ISSN: 1540-8140
Publisher: The Rockefeller University Press
Article Information
Download PDF
Copyright © 1970 by The Rockefeller University Press
Received Day: 12 Month: 8 Year: 1969
Revision Received Day: 15 Month: 10 Year: 1969
Print publication date: Day: 1 Month: 3 Year: 1970
Volume: 44 Issue: 3
First Page: 592 Last Page: 610
ID: 2107981
PubMed Id: 5415239

ELECTRICAL COUPLING BETWEEN EMBRYONIC CELLS BY WAY OF EXTRACELLULAR SPACE AND SPECIALIZED JUNCTIONS
M. V. L. Bennett
J. P. Trinkaus
From the Department of Anatomy, Albert Einstein College of Medicine, New York, New York 10461, the Department of Biology, Yale University, New Haven, Connecticut 06520, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543


Article Categories:
  • Article


Previous Document:  Biogenesis of chloroplast membranes. V. A radioautographic study of membrane growth in a mutant of C...
Next Document:  Changes in chemical composition of thylakoid membranes during greening of the y-1 mutant of Chlamydo...