Document Detail


Electrical amygdala kindling.
MedLine Citation:
PMID:  21956808     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This unit describes a method of electrical amygdala kindling in the rat. This procedure requires mastery of stereotaxic electrode implantation which is not covered in the current unit. Also, the investigator must have a sound knowledge of electronics and computing. The text gives instructions on how to render rats epileptic, how to determine the effects of compounds in kindled rats, and how to analyze the data. Results with three reference substances are illustrated. These substances are used in the clinic and give robust results in kindling.
Authors:
N Dürmüller; R D Porsolt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.]     Volume:  Chapter 5     ISSN:  1934-8290     ISO Abbreviation:  Curr Protoc Pharmacol     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2011-09-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9717249     Medline TA:  Curr Protoc Pharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  Unit5.33     Citation Subset:  IM    
Affiliation:
Porsolt and Partners Pharmacology, Boulogne Billancourts, France.
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