| Electrical Activity of the Mouse Pulmonary Vein Myocardium. | |
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MedLine Citation:
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PMID: 22785034 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We recorded the electrical activity from the myocardial layer of isolated mouse pulmonary veins with the glass microelectrode technique. Spontaneous electrical activity was observed in about half of the preparations, which appeared either as constant firing or as repetitive bursts. Noradrenaline enhanced, while acetylcholine reduced, automatic activity. The action potentials evoked in quiescent preparations showed a resting membrane potential less negative than the atria and an extremely rapid early repolarization followed by a late plateau. The present study revealed that the mouse pulmonary vein myocardium shows diverse electrical activity, which is influenced by autonomic neurotransmitters. |
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Authors:
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Yayoi Tsuneoka; Yuka Kobayashi; Yoriko Honda; Iyuki Namekata; Hikaru Tanaka |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-29 |
Journal Detail:
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Title: Journal of pharmacological sciences Volume: - ISSN: 1347-8648 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-7-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101167001 Medline TA: J Pharmacol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pharmacology, Toho University Faculty of Pharmaceutical Sciences, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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