Document Detail


Elective transfer of two embryos: reduction of multiple gestations while maintaining high pregnancy rates.
MedLine Citation:
PMID:  17186398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine if the elective transfer of two embryos reduced the incidence of multiple gestations while maintaining high pregnancy rates.
METHODS: IVF patients and recipients of oocyte donation with an elective day-3 transfer of 2 or 3 embryos were studied.
RESULT(S): In IVF, the elective transfer of 2 embryos resulted in similar pregnancy rate but significantly reduced the overall incidence of multiple gestations (20% versus 39%) when compared to the elective transfer of 3 embryos. Twin gestations decreased from 28% to 19%, and triplets significantly decreased from 9% to 1%. In oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rate but also significantly reduced the overall incidence of multiple gestations (26% versus 48%), with twins decreasing from 34% to 24%, and with a significant reduction of triplets (13% versus 2%).
CONCLUSIONS: In IVF and oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rates and significantly reduced multiple gestation rates when compared to the elective transfer of 3 embryos.
Authors:
Donna Dowling-Lacey; Estella Jones; Jacob Mayer; Silvina Bocca; Laurel Stadtmauer; Sergio Oehninger
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-12-22
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  24     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-03-28     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Embryo Transfer*
Female
Fertilization in Vitro
Humans
Oocyte Donation
Pregnancy
Pregnancy Rate
Pregnancy, Multiple / statistics & numerical data*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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