| Elective single cleavage-stage embryo transfer need not result in lower pregnancy rates compared to double cleavage-stage embryo transfer. | |
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MedLine Citation:
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PMID: 20666945 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To confirm whether women who choose to have one fresh embryo transferred and one frozen-and-thawed embryo when needed can dramatically reduce the possibility of a multifetal pregnancy while giving themselves a better chance of achieving pregnancy. METHODS: We enrolled 685 patients who were undergoing assisted reproductive technology (ART) treatment at our clinic between January 2005 and December 2008. None of the patients had a history of ART treatment, and they received either a double-embryo transfer (DET) or single-embryo transfer (SET) during this period. The outcomes of the ART and the pregnancy rates per patient were evaluated for both groups and comparisons were made. RESULTS: The mean age was 35.7 +/- 0.2 years (mean +/- standard error of the mean) for all patients (n = 583) who received a fresh embryo cycle of DET. In contrast, the mean age (34.3 +/- 0.4) of all patients (n = 102) who received a fresh- or thawed-embryo transfer cycle of SET was significantly younger than the average age in the DET group (P < 0.05). The per-patient overall pregnancy rate in the SET group was an estimated 35.3%, which was significantly higher than that in the DET group (P = 0.02). However, the multifetal pregnancy rate for the DET group was significantly higher than that for the SET group (P < 0.01). CONCLUSION: We demonstrated that women who choose to have one fresh embryo transferred and one frozen-and-thawed embryo when needed, can dramatically reduce their possibility of a multifetal pregnancy while giving themselves a better chance of achieving pregnancy. |
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Authors:
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Koji Nakagawa; Yayoi Nishi; Rie Sugiyama; Yasushi Kuribayashi; Rikikazu Sugiyama; Masato Inoue |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: 36 ISSN: 1447-0756 ISO Abbreviation: J. Obstet. Gynaecol. Res. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-29 Completed Date: 2010-11-04 Revised Date: 2012-01-19 |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: Australia |
Other Details:
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Languages: eng Pagination: 777-82 Citation Subset: IM |
Affiliation:
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Division of Reproductive Medicine, Sugiyama Clinic, Setagaya, Tokyo, Japan. koji@sugiyama.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chi-Square Distribution Embryo Transfer / methods* Female Fertilization in Vitro Humans Pregnancy Pregnancy Rate Pregnancy, Multiple Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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