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Elective sigmoid colectomy for diverticular disease: Laparoscopic versus open surgery: A systematic review.
MedLine Citation:
PMID:  21689339     Owner:  NLM     Status:  Publisher    
Aim:  A meta-analysis of nonrandomised studies and one randomised trial was conducted to compare laparoscopic surgery with open surgery in the elective treatment of patients with diverticular disease. Method:  Published randomised and controlled clinical trials that directly compared elective open (OSR) with laparoscopic surgical resection (LSR) in patients with diverticular disease were identified using the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE. End points included 30 day mortality and morbidity and were compared by determining the relative risk ratio, odds ratio, and the absolute effects. Results:  Eleven nonrandomised studies of 1,430 patients were identified and included in the meta-analysis. There was only one randomised study, which included 104 patients. The meta-analysis suggested that elective LSR was a safe and appropriate option for patients with diverticular disease and was associated with lower overall morbidity (P=0.01) and minor complication rate (P=0.008). Conclusion:  The results of the non-randomised study generally agreed with those of the randomised study, except for the incidence of minor complications, which was higher in both the LSR and OSR groups of the randomised study. In this study, the high overall morbidity of 42.3% reported in the LSR group is a cause for concern.
R Cirocchi; E Farinella; S Trastulli; F Sciannameo; R A Audisio
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-16
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  -     ISSN:  1463-1318     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 The Association of Coloproctology of Great Britain and Ireland.
Department of General Surgery, S. Maria Hospital, 1 Tristano Joannuccio, 05100 Terni, University of Perugia, Italy Department of Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Foundation Trust, London, UK Department of Surgery, St Helens Hospital, Marshalls Cross Road, WA9 3DA St Helens, University of Liverpool, United Kingdom.
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