| Elective neck dissection versus observation in primary parotid carcinoma. | |
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MedLine Citation:
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PMID: 15746848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the efficacy of elective neck dissection in the clinically negative neck of patients with primary carcinoma of the parotid gland. Study design and setting A retrospective analysis was undertaken at a university Department of Otorhinolaryngology-Head and Neck Surgery on 83 previously untreated patients with primary carcinoma of the parotid gland and a clinically negative neck. The reliability of fine needle aspiration cytology, frozen section, and the clinico-pathologic findings of patients with occult neck metastases were analyzed. The regional recurrence rate and the outcome were compared among 2 groups; one with elective neck dissection (N = 41) and one without elective neck dissection (N = 42). RESULTS: The diagnosis of malignancy was known preoperatively in 59 (71%) cases, the exact histologic tumor type in 36 (43%) and the grade in 37 (44%) of 83 cases. Occult metastases were detected in 8 (20%) of 41 cNO patients, in 5 cases associated with a high-grade and in 3 cases with a low-grade carcinoma. Recurrence of disease developed in 5 (12%) patients in the elective neck dissection group and in 11 (26%) patients in the observation group. All of the 7 neck recurrences occurred in the observation group. The 5-year actuarial and disease-free survival rate was 80% and 86% for patients with elective neck dissection and 83% and 69% for patients without neck dissection. Conclusion and significance A routine elective neck dissection is suggested in all patients with primary carcinoma of the parotid gland. The efficacy of elective neck dissection, nevertheless, has never been evaluated prospectively. |
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Authors:
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P Zbären; J Schüpbach; M Nuyens; E Stauffer |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 132 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-03-04 Completed Date: 2005-04-14 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: United States |
Other Details:
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Languages: eng Pagination: 387-91 Citation Subset: IM |
Affiliation:
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Department of Oto-Rhino-Laryngology, Head, and Neck Surgery, University Hospital, Berne, Switzerland. zbaeren@insel.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Needle Carcinoma / pathology*, surgery* Frozen Sections Humans Middle Aged Neck Dissection* Parotid Neoplasms / pathology*, surgery* Reproducibility of Results Retrospective Studies Surgical Procedures, Elective |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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