Document Detail


Elective cesarean section: its impact on neonatal respiratory outcome.
MedLine Citation:
PMID:  18456075     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Physiologic events in the last few weeks of pregnancy coupled with the onset of spontaneous labor are accompanied by changes in the hormonal milieu of the fetus and its mother, resulting in preparation of the fetus for neonatal transition. Rapid clearance of fetal lung fluid is a key part of these changes, and is mediated in large part by transepithelial sodium reabsorption through amiloride-sensitive sodium channels in the alveolar epithelial cells, with only a limited contribution from mechanical factors and Starling forces. This article discusses the respiratory morbidity associated with elective cesarean section, the physiologic mechanisms underlying fetal lung fluid absorption, and potential strategies for facilitating neonatal transition when infants are delivered by elective cesarean section before the onset of spontaneous labor.
Authors:
Ashwin Ramachandrappa; Lucky Jain
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  35     ISSN:  0095-5108     ISO Abbreviation:  Clin Perinatol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-05     Completed Date:  2008-08-14     Revised Date:  2014-09-18    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  373-93, vii     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Absorption
Body Fluids / metabolism
Cesarean Section / adverse effects*,  trends
Choice Behavior
Female
Humans
Infant, Newborn
Lung / embryology
Pregnancy
Respiratory Distress Syndrome, Newborn / etiology*,  prevention & control
Surgical Procedures, Elective*
Grant Support
ID/Acronym/Agency:
R01 HL063306/HL/NHLBI NIH HHS; R01 HL063306-02/HL/NHLBI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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