Document Detail


Elastography in hepatology.
MedLine Citation:
PMID:  18080057     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A common characteristic of all chronic liver diseases is the occurrence and progression of fibrosis toward cirrhosis. Consequently, liver fibrosis assessment plays an important role in hepatology. Besides its importance for prognosis, determining the level of fibrosis reveals the natural history of the disease and the risk factors associated with its progression, to guide the antifibrotic action of different treatments. Currently, in clinical practice, there are three available methods for the evaluation of liver fibrosis: liver biopsy, which is still considered to be the 'gold standard'; serological markers of fibrosis and their mathematical combination - suggested in recent years to be an alternative to liver biopsy - and, more recently, transient elastography (TE). TE is a new, simple and noninvasive method used to measure liver stiffness. This technique is based on the progressing speed of an elastic shear wave within the liver. Currently, there are only a few studies that have evaluated TE effectiveness in chronic liver diseases, mostly in patients infected with the hepatitis C virus. Further studies are needed in patients with chronic liver disease, to assess the effectiveness of the fibrosis treatment.
Authors:
L Abenavoli; C Corpechot; R Poupon
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Canadian journal of gastroenterology = Journal canadien de gastroenterologie     Volume:  21     ISSN:  0835-7900     ISO Abbreviation:  Can. J. Gastroenterol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-14     Completed Date:  2008-03-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8807867     Medline TA:  Can J Gastroenterol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  839-42     Citation Subset:  IM    
Affiliation:
Università Cattolica del Sacro Cuore, Rome, Italy. l.abernavoli@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Elasticity Imaging Techniques / methods*
Gastroenterology / methods*
Humans
Liver Diseases / ultrasonography*
Reproducibility of Results
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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