| Elastin-laminin receptor and abdominal aortic aneurysms. New subject to study? A review. | |
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MedLine Citation:
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PMID: 11428169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abdominal aortic aneurysms and their management remain a significant health problem that is likely to assume greater importance with the expansion of the elderly population. Elastin fibres degradation and extracellular matrix remodelling seems to be the basic process in aneurysm formation. Recent investigations revealed the principal role of elastin-laminin receptor in extracellular matrix remodelling in aging and atherosclerosis. The correlation between events observed in animal aneurysm models, human aneurysms and in experiments on elastin-laminin receptor properties was discussed to propose the hypothesis about the role of elastin peptides and elastin-laminin receptor in aortic aneurysm formation. |
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Authors:
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M Kunecki; A Nawrocka |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pathologie-biologie Volume: 49 ISSN: 0369-8114 ISO Abbreviation: Pathol. Biol. Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-06-28 Completed Date: 2001-07-26 Revised Date: 2005-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0265365 Medline TA: Pathol Biol (Paris) Country: France |
Other Details:
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Languages: eng Pagination: 333-8 Citation Subset: IM |
Affiliation:
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Department of General and Vascular Surgery, Medical University of Lodz, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging Animals Aortic Aneurysm, Abdominal / etiology*, pathology Arteriosclerosis / etiology Elastin / metabolism Extracellular Matrix / chemistry Humans Receptors, Cell Surface* / physiology Receptors, Laminin* / physiology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Cell Surface; 0/Receptors, Laminin; 0/elastin-binding proteins; 9007-58-3/Elastin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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