Document Detail


Elastic properties of the rat respiratory system related to age.
MedLine Citation:
PMID:  2967507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The experiments were performed on male rats of the Wistar strain under urethane anaesthesia (1.3 g/kg i.p.). Changes of oesophageal and tracheal pressures were registered in a group of 30 spontaneously breathing, supine rats, of 295 +/- 13 g average body weight during lung inflations with 1-5 ml of air. In another group of 25 rats of 70 +/- 6 g average body weight (young rats) we made the measurements during inflation with volumes 0.5-2 ml. The measurements were also performed in a group of 10 paralyzed, ventilated rats with 347 +/- 24 g average body weight and inflations 1-5 ml. Compliance of the lungs (CL), chest wall (CW) and of the respiratory system (Crs) was calculated from the linear part of the pressure-volume curve during inflation. The results indicate: 1. Cw is significantly (p less than 0.001) higher in young (134.7 ml.kPa-1.kg-1) than in adult rats (44.1 ml.kPa-1.kg-1). CL (related to body weight) is not significantly different in young and adult rats. 2. Cw is significantly (p less than 0.001) higher than CL. 3. No difference was observed in CLs Cw and Crs between paralyzed and spontaneously breathing animals.
Authors:
F Palecek; E Jezová
Related Documents :
12676737 - Pth increases renal 25(oh)d3-1alpha -hydroxylase (cyp1alpha) mrna but not renal 1,25(oh...
12457047 - Effect of age in rats following middle cerebral artery occlusion.
15176087 - Age-related changes in the expression of axonal and glial group i metabotropic glutamat...
9715047 - Adaptation to water depletion in the newborn rat--immunocytochemical localization of aq...
40707 - The effect of methylprednisolone on hepatic oxygen supply and plasma lactate and glucos...
10727707 - Morphine attenuates the effects of juvenile isolation in rats.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiologia Bohemoslovaca     Volume:  37     ISSN:  0369-9463     ISO Abbreviation:  Physiol Bohemoslov     Publication Date:  1988  
Date Detail:
Created Date:  1988-07-11     Completed Date:  1988-07-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0175317     Medline TA:  Physiol Bohemoslov     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  39-48     Citation Subset:  IM    
Affiliation:
Institute of Pathological Physiology, Faculty of Paediatrics, Charles University, Prague.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aging / physiology*
Animals
Elasticity
Esophagus / physiology
Lung Compliance*
Male
Pressure
Rats
Rats, Inbred Strains
Respiratory Physiological Phenomena*
Trachea / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Collagen in the aortae of spontaneously hypertensive (SHR) rats.
Next Document:  Circaseptan rhythm of corticosterone and lipids in the serum of male rats.