| Elastic network models: theoretical and empirical foundations. | |
| | |
MedLine Citation:
|
PMID: 23034765 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Fifteen years ago, Monique Tirion showed that the low-frequency normal modes of a protein are not significantly altered when nonbonded interactions are replaced by Hookean springs, for all atom pairs whose distance is smaller than a given cutoff value. Since then, it has been shown that coarse-grained versions of Tirion's model are able to provide fair insights on many dynamical properties of biological macromolecules. In this chapter, theoretical tools required for studying these so-called Elastic Network Models are described, focusing on practical issues and, in particular, on possible artifacts. Then, an overview of some typical results that have been obtained by studying such models is given. |
| | |
Authors:
|
Yves-Henri Sanejouand |
Related Documents
:
|
23337315 - Fluctuations in fitness distributions and the effects of weak linked selection on seque... 9358495 - Transient data stream dissociation in computerized data acquisition system masquerading... 1957875 - The dimension of chaos in the fetal heart rate. 19775975 - Ecg signal compression and classification algorithm with quad level vector for ecg holt... 7577845 - Feed-forward neural networks for secondary structure prediction. 858435 - Spline interpolation of demographic data. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Methods in molecular biology (Clifton, N.J.) Volume: 924 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2013 |
Date Detail:
|
Created Date: 2012-10-04 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
|
Languages: eng Pagination: 601-16 Citation Subset: IM |
Affiliation:
|
University of Nantes, Nantes, France, yves-henri.sanejouand@univ-nantes.fr. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Coarse-grained models for protein folding and aggregation.
Next Document: An introduction to dissipative particle dynamics.