Document Detail

Elastance-based control of a mock circulatory system.
MedLine Citation:
PMID:  11310786     Owner:  NLM     Status:  MEDLINE    
A new control strategy for a mock circulatory system (MCS) has been developed to mimic the Starling response of the natural heart. The control scheme is based on Suga's elastance model, which is implemented using nested elastance and pressure feedback control systems. The elastance control loop calculates the desired chamber pressure using a time-varying elastance function and the ventricular chamber volume signal. The pressure control loop regulates the chamber pressure according to this reference signal. Simulations and tests on MCS hardware showed that the elastance-based controller responds to changes in preload, afterload, and contractility in a manner similar to the natural heart. Since the elastance function is an arbitrary function of time, the controller allows modification of ventricular chamber contractility, giving researchers a new tool to mimic various pathological conditions which can be used in the evaluation of cardiac devices such as ventricular assist devices.
L A Baloa; J R Boston; J F Antaki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  29     ISSN:  0090-6964     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-04-19     Completed Date:  2001-08-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  244-51     Citation Subset:  IM    
Department of Electrical Engineering, University of Pittsburgh, PA, USA.
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MeSH Terms
Blood Circulation / physiology
Heart-Assist Devices
Hemodynamics / physiology
Models, Cardiovascular*
Myocardial Contraction / physiology
Stroke Volume / physiology

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