Document Detail


Elaiomycins K and L, new azoxy antibiotics from Streptomyces sp. Tü 6399*
MedLine Citation:
PMID:  23149516     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Elaiomycins K and L, two new azoxy-type antibiotics, were detected by HPLC-diode array screening in the culture filtrate extract of Streptomyces sp. Tü 6399. The structures were determined by high-resolution MS and 2-dimensional (1)H and (13)C correlated NMR spectroscopy including (15)N-NMR experiments and established these compounds as new members of the elaiomycin family. Both metabolites show a weak antibacterial activity against Bacillus subtilis and Staphylococcus lentus as well as against the phytophathogenic strain Xanthomonas campestris.The Journal of Antibiotics advance online publication, 14 November 2012; doi:10.1038/ja.2012.99.
Authors:
Niko Manderscheid; Soleiman E Helaly; Andreas Kulik; Jutta Wiese; Johannes F Imhoff; Hans-Peter Fiedler; Roderich D Süssmuth
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-14
Journal Detail:
Title:  The Journal of antibiotics     Volume:  -     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Mikrobiologisches Institut, Universität Tübingen, Tübingen, Germany.
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