Document Detail

Elaborated spaced-retrieval and prospective memory in mild Alzheimer's disease.
MedLine Citation:
PMID:  17852763     Owner:  NLM     Status:  MEDLINE    
Prospective memory, or the timely remembering of a planned action, is conceptualised as a cognitive process demanding episodic memory and executive attention. Impairments in these skills are characteristic of the cognitive decline in early Alzheimer's disease, providing an expectation of prominent prospective memory difficulties in this population, and yet surprisingly, memory performance in early Alzheimer's disease has rarely been evaluated within a prospective memory framework. In a preliminary study we demonstrated that older adults with early Alzheimer's disease (n=14), as compared to healthy older adults (n=14), were significantly impaired in a simple experimental paradigm of prospective remembering (a text-reading task). In a subsequent intervention study, we investigated the efficacy of spaced-retrieval for improving the prospective remembering performance of older adults with early Alzheimer's disease (n=16) compared to healthy older adults (n=16) under two learning conditions: a spaced-retrieval technique alone or spaced-retrieval combined with elaborated encoding of task. The majority of the Alzheimer's disease group (63%) demonstrated benefit in prospective remembering in the combined condition as compared to spaced-retrieval alone. Participants with Alzheimer's disease who demonstrated better executive attention (Trail Making- set-shifting) and/or better retrospective memory (Hopkins Verbal Learning Test-Revised- recognition) were more successful in the combined learning condition.
G J Kinsella; B Ong; E Storey; J Wallace; R Hester
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuropsychological rehabilitation     Volume:  17     ISSN:  0960-2011     ISO Abbreviation:  Neuropsychol Rehabil     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-05-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112672     Medline TA:  Neuropsychol Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  688-706     Citation Subset:  IM    
School of Psychological Science, La Trobe University, Victoria, Australia.
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MeSH Terms
Aged, 80 and over
Alzheimer Disease / physiopathology*
Memory / physiology*
Neuropsychological Tests
Space Perception / physiology*
Statistics as Topic
Statistics, Nonparametric

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