Document Detail


Eighteen months follow-up of the clinical efficacy of the high density mesh ablator (HDMA) in patients with atrial fibrillation after pulmonary vein isolation.
MedLine Citation:
PMID:  20635128     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The high density mesh ablator (HDMA), a mesh electrode catheter using radiofrequency delivery for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF), has been shown to have a high acute ablation success rate. The primary endpoint of our study was the efficacy of HDMA to maintain sinus rhythm (SR), and the secondary endpoint is its efficacy to reduce AF burden in an 18-month follow-up.
METHODS: Forty-two patients with AF [25 patients with paroxysmal AF (PAF, 59.5%), 17 patients with persistent AF (persAF, 40.5%)], were followed up with 7-day Holter monitoring and anamnestic survey at 6 and 12 months after PVI. To evaluate symptomatic AF episodes after 12 months, we used data from further hospital stays or information given by phone.
RESULTS: In 42 patients at intervals of 6 and 12 months, stable SR was documented in 7-day Holter monitoring in 18 patients (42.9%, 10/25 and 9/25 for PAF and 8/17 and 9/17 for persAF, respectively). Symptomatic episodes of AF were reported in 31 patients (73.8%, 18/25 for PAF and 13/17 for persAF). Re-ablation was performed in seven patients (3/25 for PAF and 4/17 for persAF) not yielding to stable SR. At an 18-month follow-up (12-29 months), AF recurrence persisted in all 42 patients; in four patients, a permanent pacemaker was implanted (9.5%). No complications attributable to the HDMA occurred in this series.
CONCLUSIONS: Our findings suggest that the PVI using the HDMA is a safe method but yields to a high AF recurrence rate at long-term follow-up even after a second procedure with the same tool.
Authors:
Petra Maagh; Marc van Bracht; Thomas Butz; Hans-Joachim Trappe; Axel Meissner
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-07-16
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  29     ISSN:  1572-8595     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-17     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  43-52     Citation Subset:  IM    
Affiliation:
Department of Cardiology and Angiology, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany. petra.maagh@rub.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Atrial Fibrillation / diagnosis,  surgery*
Catheter Ablation / instrumentation*,  methods
Catheters*
Cohort Studies
Electrocardiography
Electrocardiography, Ambulatory / methods*
Equipment Design
Equipment Safety
Female
Follow-Up Studies
Humans
Male
Middle Aged
Postoperative Care / methods
Pulmonary Veins / surgery*
Severity of Illness Index
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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