Document Detail

Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability.
MedLine Citation:
PMID:  20638067     Owner:  NLM     Status:  MEDLINE    
Antonis Zampelas
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Publication Detail:
Type:  Comment; Journal Article     Date:  2010-07-01
Journal Detail:
Title:  Atherosclerosis     Volume:  212     ISSN:  1879-1484     ISO Abbreviation:  Atherosclerosis     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-12-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  34-5     Citation Subset:  IM    
Agricultural University of Athens, Department of Food Science and Technology, Unit of Human Nutrition, Lera Odos 75, 11855 Athens, Greece.
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MeSH Terms
Administration, Oral
Carotid Artery Diseases / drug therapy*,  immunology,  metabolism,  surgery
Dietary Supplements*
Docosahexaenoic Acids / administration & dosage*,  blood
Drug Combinations
Eicosapentaenoic Acid / administration & dosage,  analogs & derivatives*,  blood,  metabolism
Endarterectomy, Carotid
Foam Cells / drug effects,  immunology
Gene Expression Regulation
Inflammation / drug therapy*,  immunology,  metabolism,  surgery
Inflammation Mediators / analysis
Matrix Metalloproteinases / genetics
Phospholipids / metabolism
Preoperative Care
Rupture, Spontaneous
T-Lymphocytes / drug effects,  immunology
Treatment Outcome
Reg. No./Substance:
0/Capsules; 0/Drug Combinations; 0/Inflammation Mediators; 0/Omacor; 0/Phospholipids; 1553-41-9/Eicosapentaenoic Acid; 25167-62-8/Docosahexaenoic Acids; 73310-10-8/eicosapentaenoic acid ethyl ester; EC 3.4.24.-/Matrix Metalloproteinases
Comment On:
Atherosclerosis. 2010 Sep;212(1):252-9   [PMID:  20542512 ]

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