Document Detail

Ehrlich ascites cells activate the alternative pathway of the human complement system.
MedLine Citation:
PMID:  6237046     Owner:  NLM     Status:  MEDLINE    
Incubation of Ehrlich ascites cells with normal or C1q or C2 deficient human sera results in killing of the cells. Killing occurred also in the absence of free Ca++, which supported by the fact that factor B and C3 were cleaved, leads to the conclusion that the alternative pathway of the complement system is activated on the surface of the Ehrlich ascites cells.
M Betz; G M Hänsch; M L Shin
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Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article    
Journal Detail:
Title:  Immunobiology     Volume:  166     ISSN:  0171-2985     ISO Abbreviation:  Immunobiology     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-11-14     Completed Date:  1984-11-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8002742     Medline TA:  Immunobiology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  397-402     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Ehrlich Tumor / immunology*
Cell Membrane / immunology
Complement Activation*
Complement Pathway, Alternative*
Cytotoxicity, Immunologic
Receptors, Complement
Receptors, Complement 3b
Reg. No./Substance:
0/Receptors, Complement; 0/Receptors, Complement 3b

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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