| The Ehlers-Danlos syndrome and colonic perforation. Report of a case and physiologic assessment of underlying motility disorder. | |
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MedLine Citation:
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PMID: 4064860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Ehlers-Danlos syndrome is a genetically determined disorder of connective tissue which is generally known for its features of fragile, hyperextensible skin, hypermobile joints, and tissue fragility. Less commonly, colorectal complications can occur, including bleeding, prolapse, and diverticulitis. A rare case of colonic perforation associated with Ehlers-Danlos syndrome is presented. Additionally, in vitro electromyographic studies of the colonic tissue were performed which suggested a possible link between abnormal myogenic activity and the colonic perforations. The authors recommend that treatment be either a permanent colostomy or a subtotal colectomy with anastomosis to the rectum for similar cases. |
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Authors:
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E Sigurdson; H S Stern; J Houpt; T Y el-Sharkawy; J D Huizinga |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diseases of the colon and rectum Volume: 28 ISSN: 0012-3706 ISO Abbreviation: Dis. Colon Rectum Publication Date: 1985 Dec |
Date Detail:
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Created Date: 1985-12-24 Completed Date: 1985-12-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 962-6 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Colon / physiopathology Colonic Diseases / etiology*, physiopathology, surgery Ehlers-Danlos Syndrome / complications* Electromyography Gastrointestinal Motility* Humans Intestinal Perforation / etiology*, physiopathology, surgery Male Muscle Contraction Muscle, Smooth / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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