Document Detail


Egyptian growth hormone deficient patients: demographic, auxological characterization and response to growth hormone therapy.
MedLine Citation:
PMID:  23337053     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: To study growth response to growth hormone (GH) treatment in growth hormone-deficient (GHD) patients. Patients and methods: In total, 477 GHD children were included in the study. Patients were followed up for a minimum of 1 year and up to 6 years, anthropometric assessment was performed every 3 months, while thyroid profile was followed every 6 months. Student's t-test was used for analysis of two quantitative variables. Results: Patients with complete GHD and multiple pituitary hormone deficiency were significantly shorter as expressed in their height standard deviation score (SDS), target height - height (SDS) and a more bone age delay. Patients with complete GHD showed better growth response compared with those with partial GHD in the first 2 years of therapy. Conclusion: We conclude that anthropometric assessment is the cornerstone in GHD diagnosis and follow-up, where catch up growth occurs in the first 2 years of therapy followed by a plateau.
Authors:
Nermin Salah; Soha M Abd El Dayem; Fatma El Mogy; Maha Amin; Marwa Ibrahim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-22
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  -     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-13     Citation Subset:  -    
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