Document Detail

Effort angina, normal coronary angiogram, and dynamic left ventricular obstruction.
MedLine Citation:
PMID:  17400122     Owner:  NLM     Status:  MEDLINE    
The development of dynamic left ventricular outflow tract (LVOT) obstruction (DLVOTO) during effort in patients without hypertrophic cardiomyopathy has been described only a few times and its clinical significance has not been established. This study was undertaken to determine DLVOTO during exercise in patients with angina and normal coronary arteries, and to analyze the potential mechanism involved. The study included 23 patients (60.7 +/- 7.2 years), with effort angina and normal coronary arteries who underwent exercise echocardiography. DLVOTO during exercise appeared in 7 patients (30.4%), with gradients ranging from 31.1 to 67.2 mm Hg (mean 41.3 +/- 12.6). These patients showed more symptoms (effort angina) during testing than the remaining patients (100% vs 47.3%; P = .014). LVOT size was the only predictive factor of DLVOTO (9.1 +/- 0.5 vs 10.3 +/- 1.2 mm/m(2); P = .017). In patients with angina and no epicardical coronary artery disease DLVOTO is associated with a lower LVOT size.
Fernando Cabrera-Bueno; Juan J Gómez-Doblas; Antonio Muñoz-García; José M García-Pinilla; Manuel Jiménez Navarro; Eduardo de Teresa-Galván
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  20     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-02     Completed Date:  2007-06-05     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  415-20     Citation Subset:  IM    
Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain. <>
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MeSH Terms
Blood Flow Velocity / physiology
Coronary Angiography*
Echocardiography, Doppler
Echocardiography, Stress
Heart Ventricles / physiopathology,  ultrasonography*
Microvascular Angina / complications*,  physiopathology,  radiography
Middle Aged
Myocardial Contraction / physiology
Severity of Illness Index
Stroke Volume
Ventricular Outflow Obstruction / complications*,  physiopathology,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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