Document Detail

Efficient translational rehabilitation randomised controlled trial designs using disease progress modelling and trial simulation.
MedLine Citation:
PMID:  19626555     Owner:  NLM     Status:  MEDLINE    
Given the challenges inherent in randomised trials of rehabilitation interventions, methods are required to increase trial efficiency and information yield. This paper discusses, in a non-technical manner, a class of statistical models that is particularly suited to the task of detecting potential treatment effects against a background of spontaneous change.
Rob Forsyth
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-07-16
Journal Detail:
Title:  Neuropsychological rehabilitation     Volume:  19     ISSN:  1464-0694     ISO Abbreviation:  Neuropsychol Rehabil     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-02-25     Completed Date:  2010-06-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112672     Medline TA:  Neuropsychol Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  891-903     Citation Subset:  IM    
Institute of Neuroscience, Newcastle University, UK.
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MeSH Terms
Brain Injuries / rehabilitation*
Computer Simulation
Disease Progression
Models, Statistical
Nonlinear Dynamics*
Randomized Controlled Trials as Topic / methods*
Rehabilitation / methods*
Research Design*
Translational Research / methods*

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