| Efficient and mild microwave-assisted stepwise functionalization of naphthalenediimide with alpha-amino acids. | |
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MedLine Citation:
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PMID: 16930065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Microwave dielectric heating proved to be an efficient method for the one-pot and stepwise syntheses of symmetrical and unsymmetrical naphthalenediimide derivatives of alpha-amino acids. Acid-labile side chain protecting groups are stable under the reaction conditions; protection of the alpha-carboxylic group is not required. The stepwise condensation of different amino acids resulted in high yields of unsymmetrical naphthalenediimides. The reaction proceeds without racemization and is essentially quantitative. |
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Authors:
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Paolo Pengo; G Dan Pantos; Sijbren Otto; Jeremy K M Sanders |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 71 ISSN: 0022-3263 ISO Abbreviation: J. Org. Chem. Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-08-25 Completed Date: 2007-06-27 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 7063-6 Citation Subset: IM |
Affiliation:
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University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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chemical synthesis*,
chemistry Chemistry, Organic / methods* Crystallography, X-Ray Imides Magnetic Resonance Spectroscopy Microwaves* Molecular Structure Naphthalenes Phenanthrolines / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Imides; 0/Naphthalenes; 0/Phenanthrolines; 22291-04-9/naphthalenediimide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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