Document Detail

Efficient production of 2-oxobutyrate from 2-hydroxybutyrate by using whole cells of Pseudomonas stutzeri strain SDM.
MedLine Citation:
PMID:  20080995     Owner:  NLM     Status:  MEDLINE    
2-Oxobutyrate is an important intermediate in the chemical, drug, and food industries. Whole cells of Pseudomonas stutzeri SDM, containing NAD-independent lactate dehydrogenases, effectively converted 2-hydroxybutyrate into 2-oxobutyrate. Under optimal conditions, the biocatalytic process produced 2-oxobutyrate at a high concentration (44.4 g liter(-1)) and a high yield (91.5%).
Chao Gao; Wen Zhang; Chuanjuan Lv; Lixiang Li; Cuiqing Ma; Chunhui Hu; Ping Xu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-15
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  76     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-24     Completed Date:  2010-05-18     Revised Date:  2013-05-31    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1679-82     Citation Subset:  IM    
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People's Republic of China.
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MeSH Terms
Biotechnology / methods
Butyrates / metabolism*
Hydroxybutyrates / metabolism*
L-Lactate Dehydrogenase / metabolism
Pseudomonas stutzeri / metabolism*
Reg. No./Substance:
0/Butyrates; 0/Hydroxybutyrates; 600-18-0/alpha-ketobutyric acid; EC Dehydrogenase

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