Document Detail

Efficacy and tolerability of long-term treatment with vagus nerve stimulation in adolescents and adults with refractory epilepsy and learning disabilities.
MedLine Citation:
PMID:  21035358     Owner:  NLM     Status:  MEDLINE    
The long-term effects of vagus nerve stimulation (VNS) on seizure frequency were studied in 50 patients with epilepsy and learning disabilities. Mean observation time was 4.6 years. At follow-up, none of the patients was seizure-free, 25% had more than 50% seizure reduction, and 46% had some seizure reduction, but less than 50%. The discontinuation rate was 18%. Our results indicate that, like antiepileptic drugs, VNS does not have such a good seizure-reducing effect in patients with epilepsy and learning disabilities compared with the general epilepsy population.
Caroline Lund; Hrisimir Kostov; Berit Blomskjøld; Karl O Nakken
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-10-29
Journal Detail:
Title:  Seizure     Volume:  20     ISSN:  1532-2688     ISO Abbreviation:  Seizure     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-03     Completed Date:  2011-11-09     Revised Date:  2014-10-21    
Medline Journal Info:
Nlm Unique ID:  9306979     Medline TA:  Seizure     Country:  England    
Other Details:
Languages:  eng     Pagination:  34-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
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MeSH Terms
Epilepsy / complications*,  psychology,  therapy*
Follow-Up Studies
Learning Disorders / complications*,  psychology,  therapy*
Middle Aged
Treatment Outcome
Vagus Nerve Stimulation / methods,  trends*
Young Adult

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