| Efficacy and tolerability of long-term treatment with vagus nerve stimulation in adolescents and adults with refractory epilepsy and learning disabilities. | |
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MedLine Citation:
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PMID: 21035358 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The long-term effects of vagus nerve stimulation (VNS) on seizure frequency were studied in 50 patients with epilepsy and learning disabilities. Mean observation time was 4.6 years. At follow-up, none of the patients was seizure-free, 25% had more than 50% seizure reduction, and 46% had some seizure reduction, but less than 50%. The discontinuation rate was 18%. Our results indicate that, like antiepileptic drugs, VNS does not have such a good seizure-reducing effect in patients with epilepsy and learning disabilities compared with the general epilepsy population. |
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Authors:
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Caroline Lund; Hrisimir Kostov; Berit Blomskjøld; Karl O Nakken |
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Publication Detail:
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Type: Journal Article Date: 2010-10-29 |
Journal Detail:
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Title: Seizure : the journal of the British Epilepsy Association Volume: 20 ISSN: 1532-2688 ISO Abbreviation: Seizure Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306979 Medline TA: Seizure Country: England |
Other Details:
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Languages: eng Pagination: 34-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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National Centre for Epilepsy, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway. Caroline.lund@epilepsy.no |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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