Document Detail

Efficacy of sphenopalatine ganglion blockade in 66 patients suffering from cluster headache: a 12- to 70-month follow-up evaluation.
MedLine Citation:
PMID:  9384398     Owner:  NLM     Status:  MEDLINE    
This study was conducted to evaluate the efficacy, based on 12- to 70-month follow-up data, of radiofrequency (RF) lesions of the sphenopalatine ganglion made in patients suffering from cluster headache. Sixty-six patients suffering from either episodic (Group A, 56 patients) or chronic (Group B, 10 patients) cluster headache who were not responsive to pharmacological management were treated by RF lesioning in the sphenopalatine ganglion. Complete relief of pain was achieved in 34 (60.7%) of 56 patients in Group A and in three (30%) of 10 patients in Group B. No relief was found in eight patients (14.3%) in Group A and in four (40%) in Group B. The mean time of follow up was 29.1 +/- 10.6 months in Group A and 24 +/- 9.7 months in Group B, ranging from 12 to 70 months. With regard to side effects and complications, temporary postoperative epistaxis was observed in eight patients and a cheek hematoma in 11 patients; a partial RF lesion of the maxillary nerve was inadvertently made in four patients. Nine patients complained of hypesthesia of the palate, which disappeared in all cases within 3 months. The authors conclude that RF lesioning in the sphenopalatine ganglion via the infrazygomatic approach may be performed in patients suffering from cluster headache that does not respond to pharmacological therapy.
M Sanders; W W Zuurmond
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  87     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1997-12-18     Completed Date:  1997-12-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  876-80     Citation Subset:  AIM; IM    
Department of Anesthesiology, Spaarne Hospital, Haarlem, The Netherlands.
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MeSH Terms
Acute Disease
Autonomic Nerve Block / adverse effects,  methods*
Catheter Ablation / adverse effects
Chronic Disease
Cluster Headache / drug therapy,  surgery*
Epistaxis / etiology
Evaluation Studies as Topic
Follow-Up Studies
Ganglia, Parasympathetic / surgery*
Ganglionectomy / adverse effects
Hematoma / etiology
Hypesthesia / etiology
Maxillary Nerve / injuries
Palate / innervation
Remission Induction
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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