Document Detail


Efficacy and safety of oxum in treatment of chronic wounds.
MedLine Citation:
PMID:  20509477     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chronic wounds represent a major health burden contributing to substantial mortality, morbidity and costs. Several new treatment options are currently available, which has revolutionised the management of chronic wounds. The present study is a single centre, prospective, clinical trial comparing oxum (super oxidised water) and betadine as a topical treatment of chronic wounds conducted in 30 Indian patients, with 15 patients in each group. At the end of the study, there was a significant reduction in primary parameters such as wound area and microbial colony count in oxum treated group compared to betadine group. However, both the oxum and betadine treated group showed a similar results when the secondary parameters such as oedema, erythema and granulation tissue were considered. Oxum was better tolerated than betadine. It can be concluded that use of oxum (super oxidised water) is a novel technological innovation in the therapy of chronic wounds. Oxum has been shown to be effective, well tolerated and superior to betadine in wound care.
Authors:
Suhas V Abhyankar; Veena Venkatesh; Savita Karnad; K P Kulkarni; Manpreet Juneja; Bheem Singh Nanda; T Saifulla
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the Indian Medical Association     Volume:  107     ISSN:  0019-5847     ISO Abbreviation:  J Indian Med Assoc     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-07-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505608     Medline TA:  J Indian Med Assoc     Country:  India    
Other Details:
Languages:  eng     Pagination:  904-6     Citation Subset:  IM    
Affiliation:
Department of Plastic Surgery, Dr RN Cooper Hospital, Mumbai 400056.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Anti-Infective Agents, Local / adverse effects,  therapeutic use*
Chronic Disease
Colony Count, Microbial
Female
Health Status Indicators
Humans
Hydrogen Peroxide / adverse effects,  therapeutic use*
Male
Oxidants / adverse effects,  therapeutic use*
Povidone-Iodine / adverse effects,  therapeutic use*
Prospective Studies
Wound Healing / drug effects
Wounds and Injuries / drug therapy*,  microbiology
Chemical
Reg. No./Substance:
0/Anti-Infective Agents, Local; 0/Oxidants; 0/superoxidized water; 25655-41-8/Povidone-Iodine; 7722-84-1/Hydrogen Peroxide

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