Document Detail

Efficacy of a pre-thickened infant formula: a multicenter, double-blind, randomized, placebo-controlled parallel group trial in 104 infants with symptomatic gastroesophageal reflux.
MedLine Citation:
PMID:  12921449     Owner:  NLM     Status:  MEDLINE    
To evaluate a pre-thickened formula (Enfamil AR) for regurgitant gastroesophageal reflux, 104 infants were enrolled in a 5-week, multicenter, double-blind, randomized, placebo-controlled parallel group trial. The Enfamil AR group showed greater symptom reduction by the end of the first week: percent feedings with any regurgitation (p = 0.045), total regurgitation volume score (p = 0.035), and percent feedings with choke-gag-cough (p = 0.004). The most symptomatic infants at baseline had a reduction in trouble sleeping significantly with Enfamil AR by the end of the study (p = 0.030). This formula flows through a standard nipple, reduces regurgitation and choking-gagging-coughing within a week, and improves sleep in the most symptomatic babies by 5 weeks, without causing constipation.
Jon A Vanderhoof; J Roberto Moran; Cheryl L Harris; Kimberly L Merkel; Susan R Orenstein
Related Documents :
12193679 - The effects of dietary nucleotides on intestinal blood flow in preterm infants.
3564969 - Milk protein intake in the term infant. i. metabolic responses and effects on growth.
8086719 - Faecal short chain fatty acids in breast-fed and formula-fed babies.
17559329 - Effects of breast milk and milk formula diets on synthesized speech sound-induced event...
7762449 - Faecal flora in the newborn. effect of lactoferrin and related nutrients.
19172129 - Galacto-oligosaccharides are bifidogenic and safe at weaning: a double-blind randomized...
12193679 - The effects of dietary nucleotides on intestinal blood flow in preterm infants.
1599589 - Mortality of american indian and alaska native infants.
7209799 - Congenital diaphragmatic hernia: pathophysiology and pharmacologic support.
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical pediatrics     Volume:  42     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-08-18     Completed Date:  2003-12-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  483-95     Citation Subset:  AIM; IM    
Joint Section of Pediatric Gastroenterology and Nutrition, University of Nebraska Medical Center and Creighton University, Omaha, Nebraska, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Double-Blind Method
Gastroesophageal Reflux / diet therapy*
Infant Formula*
Infant, Newborn
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A review of common pediatric lip lesions: herpes simplex/recurrent herpes labialis, impetigo, mucoce...
Next Document:  Attention deficit hyperactivity disorder in elementary school children in Rhode Island: associated p...