Document Detail

Efficacy of percutaneous transluminal renal angioplasty with stent in elderly male patients with atherosclerotic renal artery stenosis.
MedLine Citation:
PMID:  23091375     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Percutaneous transluminal renal angioplasty with stent implantation (PTRAS) has become the treatment of choice for atherosclerotic renal artery stenosis (ARAS). This study evaluates the long-term effects of PTRAS on hypertension and renal function in elderly patients with ARAS.
METHODS: We conducted a retrospective cohort study of all patients who underwent PTRAS in the geriatric division of a tertiary medical center during the period 2003-2010. The clinical data were extracted from the medical records of each patient. Changes in blood pressure, antihypertensive treatment, and estimated glomerular filtration rate were analyzed before and after PTRAS.
RESULTS: Eighty-six stents in 81 elderly patients were placed successfully. The average age of the patients was 76.2 years (65-89 years). Mean follow-up was 31.3 months (range 12 -49 months). There was a significant decrease in both systolic and diastolic blood pressure at the third day after the PTRAS procedure and the reduction in blood pressure was constant throughout the follow-up period until 36 months after PTRAS. However, there was no marked benefit to renal function outcome during the follow-up period. The incidence of contrast-induced nephropathy was 9.9% in this study group. The rate of renal artery restenosis was 14.8%. The survival rate was 96.3% for 4 years after the procedure.
CONCLUSION: It is beneficial to control blood pressure in elderly patients with ARAS up to 36 months after a PTRAS procedure. However, their renal function improvement is limited.
Jiahui Zhao; Qingli Cheng; Xiaoying Zhang; Meihua Li; Sheng Liu; Xiaodan Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-10-12
Journal Detail:
Title:  Clinical interventions in aging     Volume:  7     ISSN:  1178-1998     ISO Abbreviation:  Clin Interv Aging     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-23     Completed Date:  2013-02-06     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  101273480     Medline TA:  Clin Interv Aging     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  417-22     Citation Subset:  IM    
Department of Geriatric Nephrology, Chinese PLA General Hospital, Beijing, China.
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MeSH Terms
Aged, 80 and over
Angioplasty / methods*
Atherosclerosis / epidemiology*,  surgery*
Blood Pressure
Diabetes Complications
Fluid Therapy
Kidney / blood supply
Kidney Function Tests
Renal Artery Obstruction / epidemiology*,  surgery*,  therapy
Retrospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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