Document Detail


Efficacy of patient education and supervised exercise vs patient education alone in patients with hip osteoarthritis: a single blind randomized clinical trial.
MedLine Citation:
PMID:  20633669     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To compare the efficacy of patient education and supervised exercise with that of patient education alone for the management of pain in patients with hip osteoarthritis (OA).
DESIGN: Single blind randomized clinical trial.
SETTING: Recruitment of patients from hospitals, primary health care and advertisement, Oslo, Norway.
PARTICIPANTS: 109 patients with radiographic and symptomatic hip OA with mild to moderate symptoms.
INTERVENTIONS: Patient education (PE). Patient education and supervised exercise (PE+SE).
PRIMARY OUTCOME MEASURE: The pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC pain).
RESULTS: No significant between group differences were found for WOMAC pain over the 16-month follow-up. Significant improvements were found for the secondary outcome WOMAC physical function (P=0.011) in the group receiving PE+SE compared to the group receiving PE only. No significant differences were found for WOMAC stiffness, the SF-36 subscales or the activity scale. The effect sizes (95% confidence interval) for WOMAC pain were -0.26 (0.11, -0.64), -0.35 (0.07, -0.77), and -0.30 (0.15, -0.75), and for WOMAC physical function -0.29 (0.09, -0.67), -0.48 (-0.06, -0.91), and -0.47 (-0.02, -0.93) at 4, 10 and 16 months, respectively, in favor of the group receiving both PE and SE. All patients attended the three-session PE program, and 75% performed ≥16 sessions of the 12-week SE program.
CONCLUSION: The study could not demonstrate a significant difference in pain reduction over time between PE+SE vs PE alone. Adding SE to PE may improve physical function, but the magnitude of possible benefit is unknown as the 95% confidence intervals around the mean difference were wide.
TRIAL REGISTRATION: Clinical Trials NCT00319423.
Authors:
L Fernandes; K Storheim; L Sandvik; L Nordsletten; M A Risberg
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2010-07-13
Journal Detail:
Title:  Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society     Volume:  18     ISSN:  1522-9653     ISO Abbreviation:  Osteoarthr. Cartil.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9305697     Medline TA:  Osteoarthritis Cartilage     Country:  England    
Other Details:
Languages:  eng     Pagination:  1237-43     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Norwegian Research Center for Active Rehabilitation (NAR), Department of Orthopedics, Oslo University Hospital, Oslo, Norway. linda.fernandes@medisin.uio.no
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00319423
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